Black Cohosh - American Family Physician
نویسنده
چکیده
Uses and Efficacy Currently, the primary use of black cohosh extract is for alleviation of menopausal symptoms. The American College of Obstetrics and Gynecology guidelines on the use of botanicals for the management of menopausal symptoms support this use for up to six months, especially in treating the symptoms of sleep and mood disturbance, and hot flushes. [Evidence level C, consensus/expert guidelines] At least eight studies of black cohosh therapy for menopausal symptoms, involving approximately 2,000 women, have been published, most of them in German. Many of these studies used an estrogen product in the control group, and most of the trials used standardized outcome measures such as the Kupperman Menopause Index and the Hamilton Anxiety Scale. Almost all of these studies demonstrate efficacy in patients taking black cohosh extract similar to that of estrogen in the treatment of neurovegetative menopausal symptoms. Unfortunately, most of these studies are open trials and lack blinding and long-term followup, making it difficult to draw definitive conclusions from their results. As with other herbal medicines believed to have potential estrogenic effects, there has been T he herb black cohosh, or Actaea racemosa (formerly named Cimicifuga racemosa), is native to North America. The roots and rhizomes are widely used in the treatment of menopausal symptoms and menstrual dysfunction. Black cohosh was originally used by Native American peoples in the treatment of many conditions, especially gynecologic disorders. The most widely used and best studied commercial formulation available in the United States is Remifemin, an extract of the rhizome that is produced by a German company. Numerous other brands of black cohosh are available, but not all are standardized extracts. Black cohosh should not be confused with the blue cohosh herb (also known as Caulophyllum thalictroides), which is used for different indications and has a greater potential for toxicity.
منابع مشابه
Nonhormonal therapies for hot flashes in menopause.
Numerous reports in the medical literature and popular media have discussed the effectiveness of various nonhormonal agents in reducing menopausal hot flash symptoms. Data for these therapies are limited, and most of the studies have been conducted in women with a history of breast cancer. Selective serotonin reuptake inhibitors and venlafaxine have been shown to reduce hot flashes by 19 to 60 ...
متن کاملArchives of Internal Medicine Study Finds One Black Cohosh Effective for Treating iVIenopausal Symptoms
A July 24 review article published in the Archives of Internal Medicine (2006;166:1453-1465) concluded that alternative and complementary therapies are generally ineffective for treating menopause-related symptoms. Among the biologically based studies, only one on Remifemin® out of the four black cohosh studies reviewed was shown to be effective. "A single large trial showed a benefit for vasom...
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Hormone-related supplements (HRS), many of which contain phytoestrogens, are widely used to manage menopausal symptoms, yet their relationship with breast cancer risk has generally not been evaluated. We evaluated whether use of HRS was associated with breast cancer risk, using a population-based case-control study in 3 counties of the Philadelphia metropolitan area consisting of 949 breast can...
متن کاملAnalysis of formononetin from black cohosh (Actaea racemosa).
Black cohosh has been widely used as an herbal medicine for the treatment of symptoms related to menopause in America and Europe during the past several decades, but the bioactive constituents are still unknown. Formononetin is an isoflavone with known estrogen-like activity. This compound was first reported to be isolated from black cohosh in 1985, but subsequent research in 2002 using HPLC-PD...
متن کاملPnm-19: The Effect of Black Cohosh (CimicifugaRacemosa) on Vasomotor Symptoms in Postmenopausal Women: A Randomized Clinical Trial
Background: Hot flash is considered to be an early and common symptom of menopause. This symptom can interfere with the social and personal life of women; therefore, it demands a secure and effective intervention. Therefore, the present study aimed to determine the impact of black cohosh (Cimicifugaracemosa or actaearacemosa) on vasomotor symptoms in postmenopausal women. Materials and Methods:...
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